Computational screening of phytochemicals to block phosphoenol pyruvate carboxykinase (PEPCK), a Key enzyme in glucose metabolism.

Abstract :

Growing population, fast urbanization, rising income, increasing economic activities, changing life style and consumption pattern have been increasing the generation of solid wastes especially in urban areas of India. We assessed the generation and management of household municipal solid waste in the extension and town areas of different socioeconomic classes (low, middle and high income groups) of Tiruvarur during 2004 -2005. The parameters of demography, monthly income and area of residence varied significantly among the classes except total population of the household which varied between areas. The community practices of the households of extension area indicated that they were better in solid waste management practices than that of the town area. Totally 24 different solid wastes were segregated and among these wastes the quantity of vegetable peels followed by food wastes and fruit wastes were the dominant solid wastes. Furthermore, the mean weight of envelope, ball point pen, plastic buckets, plastic toys, other plastics, glass, medicine bottles, light bulbs, building debris, fruit peels, cattle dung and waste batteries showed significant variations between areas and among the socioeconomic classes. In both areas 100% households failed to segregate, recycle and home compost the wastes generated. Hence, we suggest the households to segregate the wastes and recycle the inorganic wastes and home compost the organic wastes and thereby reduce the quantum of waste generation. In addition, we recommend the Tiruvarur municipality to adopt effective, efficient and scientific management of solid wastes by converting them into productive resources such as input for power generation, laying of plastic roads, vermicomposting and production of organic manures.