Antimicrobial effect of probiotic food against intestinal pathogens
A food can be defined as functional if it is shown to beneficially affect one or more target functions in the body beyond adequate nutritional effects in a way that is relevant to either the state of well-being and health, or to a reduction in disease incidence. The clinical situations studied presently include diarrhea, intestinal infections and colonization by pathogenic bacteria (including Helicobacter pylori and Clostridium difficile), so two different probiotic strains Pediococcus sp and Bifidobacterium sp. cointaining Dairy based probiotic drink were checked for their clinical benefits, which showed a good reduction in the number of intestinal pathogens. When the same experiment was conducted invitro the zone of inhibition clearly showed the antimicrobial effect of the probiotic strains against the intestinal pathogens. There are many mechanisms by which probiotics enhance intestinal health, including stimulation of immunity, competition for limited nutrients, inhibition of epithelial and mucosal adherence, inhibition of epithelial invasion and production of antimicrobial substances. From the findings it is clear that probiotic cultures are efficient in the removal of colonization of intestinal pathogens to the host intestine thereby giving protection to the host body.
Probiotics, Fermented foods, colonization, Pathogens, etc.,