Impact of soil type in the production of Andrographolide

Abstract :

In pharmaceutical field, the search for compounds that have suitable properties to be used is nowadays a big challenge. Atenolol, one of the most widely used â-Blockers, clinically used as a reference drug in randomized controlled trials of hypertension. Single crystals of Atenolol have been grown successfully by slow evaporation of an ethanol/water solution. The modes of vibration of different groups present in the crystals are identified by FT-IR technique. The range and percentage of optical transmission as well as absorption are ascertained by recording UV-Vis-NIR spectrum. To understand the thermal properties, TGA and DTA were carried out. The surface morphology of the crystal were analysed by Scanning Electron Microscope. Grown crystals have been characterized using Powder X-ray diffraction and energy dispersive X-ray spectroscopy (EDAX).