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Research Article

Year : 2007 | Volume: 1 | Issue: 1 | Pages: 19-22

Hepatoprotective activity of Phyllanthus emblica Linn. extract against paracetamol-induced hepatic damage in rats.

S.Madhavan1*, R.Sivabalan, S.Ambiga2

DOI: 0

Corresponding author

S.Madhavan*

Anna University

  • 1. Anna University
  • 2. Anna University

Received on: 17/06/2015

Revised on: 17/06/2015

Accepted on: 17/06/2015

Published on: 17/06/2015

  • S.Madhavan, R.Sivabalan, S.Ambiga (2007), Hepatoprotective activity of Phyllanthus emblica Linn. extract against paracetamol-induced hepatic damage in rats.. Scientific Transactions in Environment and Technovation, 1(1): 19-22. doi: 10

Abstract

The efficacy of the medicinal plant Phyllanthus emblica Linn. to prevent paracetamol-induced hepatotoxicity in rats was examined by determining the concentrations of biochemical markers of liver enzymes Serum Glutamate Pyruvate Transaminase (SGPT), Serum Glutamate Oxaloacetate Transaminase (SGOT), Alkaline Phosphatase (ALP) and Acid Phosphatase(ACP), and triglycerides, protein, cholesterol and phospholipids in serum. Treatment with aqueous extract of fruits of Phyllanthus emblica Linn. improved the levels of biochemical molecules to near normal levels suggesting the hepatoprotective effect of this medicinal plant.

Keywords

aqueous extract, hepatoprotective activity, Phyllanthus emblica Linn.