A study on the diversity of freshwater bivalves in the rivers of Karnataka and Kerala, South India.

Abstract :

L-asparaginase is receiving the attention because of its potential use as a chemotherapeutic agent in tumour and acute lymphoblastic leukemia. In the present study an attempt has been made to produce L-asparaginase by using Streptomyces species isolated from soil. The test isolates were initially screened by rapid plate assay method for L- asparaginase production. Streptomyces showed the highest productivity of 45.2 IU/ml with a protein content of 65 µg/ml, and optimum activity at pH 7.5 and 30ÚC. This study clearly indicates that soil can provide a rich source of L-asparaginase producing actinomycetes.